Fig. 4
From: Advanced epithelial lung and gut barrier models demonstrate passage of microplastic particles
Pro-inflammatory cytokine release by lung epithelial cells or porcine colon intestinal tissue explants upon 96 or 24 h exposure, respectively, to MNP (1 mg/mL). A-B IL-6 (A) and IL-8 (B) secretion into the basolateral compartment by lung epithelial cells (MucilAir™) after 96 h (n = 3). C-F IL-6 (C), IL-8 (D), IL-1β (E) and IL-18 (F) secretion into the basolateral compartment by porcine colon tissue explants mounted in the IEBC after 24 h (n = 3–4). Data are presented as mean ± SD. * p < 0.05 compared to the control condition, calculated by one-way ANOVA (Dunnett’s multiple comparisons)