Table 6 Screening levels aligned (1 to 5,000 µm) to various TRMs, with different sensitivity analysis scenarios shown (alignment uncertainty represented lower and upper 95th percentile based on length power law value)
Reference dosea (mg·kg−1·d−1) | RSC (unitless) | DWI (L·kg−1·d−1) | Screening Levela (µg·L−1) | Mass-aligned Screening Level (particles·L−1) | Particle-aligned Screening Level (particles·L−1) | Surface area-aligned Screening Level (particles·L−1) | Specific surface-area aligned Screening Level (particles·L−1) | Volume-aligned Screening Level (particles·L−1) |
|---|---|---|---|---|---|---|---|---|
0.14 (BMD) | 0.50 | 0.022 | 3200 | 1.6 × 108 (1.5 × 108 to 1.9 × 108) | 3.1 × 109 (2.6 × 109 to 3.5 × 109) | 1.3 × 109 (1.3 × 109 to 1.3 × 109) | 6.1 × 109 (5.5 × 109 to 6.9 × 109) | 3.4 × 108 (3.4 × 109 to 3.6 × 108) |
0.024 (BMDL)b | 0.20 | 0.053 | 90 | 4.6 × 106 (4.2 × 106 to 5.2 × 106) | 8.6 × 107 (7.5 × 107 to 9.9 × 107) | 3.6 × 107 (3.6 × 107 to 3.8 × 107) | 1.7 × 108 (1.6 × 108 to 1.9 × 108) | 9.6 × 106 (9.5 × 106 to 1.0 × 107) |
0.024 (BMDL) | 0.0001 | 0.135 | 0.0018 | 91 (82 to 1.0 × 102) | 1.7 × 103 (1.5 × 103 to 1.9 × 103) | 7.1 × 102 (7.0 × 102 to 7.4 × 102) | 3.4 × 103 (3.1 × 103 to 3.8 × 103) | 1.9 × 102 (1.9 × 102 to 2.0 × 102) |