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Table 6 Screening levels aligned (1 to 5,000 µm) to various TRMs, with different sensitivity analysis scenarios shown (alignment uncertainty represented lower and upper 95th percentile based on length power law value)

From: Development and application of a health-based framework for informing regulatory action in relation to exposure of microplastic particles in California drinking water

Reference dosea
(mg·kg−1·d−1)
RSC
(unitless)
DWI
(L·kg−1·d−1)
Screening Levela
(µg·L−1)
Mass-aligned Screening Level (particles·L−1) Particle-aligned Screening Level (particles·L−1) Surface area-aligned Screening Level (particles·L−1) Specific surface-area aligned Screening Level (particles·L−1) Volume-aligned Screening Level (particles·L−1)
0.14 (BMD) 0.50 0.022 3200 1.6 × 108
(1.5 × 108 to 1.9 × 108)
3.1 × 109
(2.6 × 109 to 3.5 × 109)
1.3 × 109
(1.3 × 109 to 1.3 × 109)
6.1 × 109
(5.5 × 109 to 6.9 × 109)
3.4 × 108
(3.4 × 109 to 3.6 × 108)
0.024
(BMDL)b
0.20 0.053 90 4.6 × 106
(4.2 × 106 to 5.2 × 106)
8.6 × 107
(7.5 × 107 to 9.9 × 107)
3.6 × 107
(3.6 × 107 to 3.8 × 107)
1.7 × 108
(1.6 × 108 to 1.9 × 108)
9.6 × 106
(9.5 × 106 to 1.0 × 107)
0.024
(BMDL)
0.0001 0.135 0.0018 91
(82 to 1.0 × 102)
1.7 × 103
(1.5 × 103 to 1.9 × 103)
7.1 × 102
(7.0 × 102 to 7.4 × 102)
3.4 × 103
(3.1 × 103 to 3.8 × 103)
1.9 × 102
(1.9 × 102 to 2.0 × 102)
  1. aReference doses and screening levels reported here are derived with a composite uncertainty factor of one
  2. b”Default” parameters for screening level derivation