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Table 4 Sensitivity analyses to assess the impact of alignment method, endpoint selection and individual studies, on the threshold values calculated

From: Risk-based management framework for microplastics in aquatic ecosystems

  Food dilution Tissue translocation
Parameter Max increase (% difference) Max decrease (% difference) Max increase (% difference) Max decrease (% difference)
Polydisperse laboratory assumptions (mass, volume, surface area) + 5% −2% + 5% −15%
Bioaccessible assumptions (length, width) + 31% −53% + 32% −89%
Environmental MPs polydispersity distribution (length, volume, surface area) NA −87% + 285% −31%
Endpoint selection (all vs. fitness vs. mortality) + 628,000% NA + 2511% −38%
Study influence (leave-one-out method) + 300% −26% + 275% −47%